منابع مشابه
Substitution of another opioid for morphine. Opioid toxicity should be managed initially by decreasing the opioid dose.
Substitution of another opioid for morphine. Opioid toxicity should be managed initially by decreasing the opioid dose' BMJ, vol 317, no. 7150, pp. 81. General rights Copyright for the publications made accessible via the Edinburgh Research Explorer is retained by the author(s) and / or other copyright owners and it is a condition of accessing these publications that users recognise and abide b...
متن کاملOpioid dependence and substitution therapy: thymoquinone as potential novel supplement therapy for better outcome for methadone maintenance therapy substitution therapy
Methadone is widely being used for opioid substitution therapy. However, the administration of methadone to opioid dependent individual is frequently accompanied by withdrawal syndrome and chemical dependency develops. Other than that, it is also difficult to retain patients in the treatment programme making their retention rates are decreasing over time. This article is written to higlights th...
متن کاملSubstitution treatment for opioid addicts in Germany
BACKGROUND After a long and controversial debate methadone maintenance treatment (MMT) was first introduced in Germany in 1987. The number of patients in MMT--first low because of strict admission criteria--increased considerably since the 1990s up to some 65,000 at the end of 2006. In Germany each general practitioner (GP), who has completed an additional training in addiction medicine, is all...
متن کاملOpioid substitution: improving cost-efficiency.
Editorials 83 The United Nations Office of Drugs and Crime in its 2012 World drug report estimates that 0.6% of the world's adult population – some 27 million people – are problem users of illicit drugs. 1 This represents about 10% of all people who used illicit drugs in 2011 and suggests that most people can use drugs recreationally without becoming dependent. What makes these 10% different is...
متن کاملOpioid Receptors of the Central Amygdala and Morphine-Induced Antinociception
The amygdala is a forebrain region, which is known as a modulator of pain sensation. The amygdala, particularly the central nucleus, has high concentrations of enkephalins relative to dynorphins and has high concentrations of opioid receptors. We here studied the role of central nuclei of amygdala in morphine antinociception. Methods: In this study, we used 130 male Wistar rats (200- 250g). Bil...
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ژورنال
عنوان ژورنال: BMJ
سال: 1998
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.317.7150.81